Measurement of total body water with deuterium oxide

The measurement of total body water in living pigs by deuterium oxide dilution and its relation to body composition.

I. Deuterium oxide was used to estmate body water in twenty-four pigs of widely differing body composition and of average weight 83.9 kg. 2. After infusion of the isotope, blood samples were collected every 30 min for 4 h. The resulting plasma was purified by a heat-distillation procedure, after which it was analysed for D,O by infrared spectroscopy. 3. Approximately 24 h after infusion of the ...

The measurement of total body water in the human subject by deuterium oxide dilution; with a consideration of the dynamics of deuterium distribution.

The interpretation of fluctuations in body weight and changes in the state of hydration requires a knowledge of the total amount of water in the organism. This investigation has been directed towards the perfection of a method for measurement of the total body water in the human subject. The increasing availability and lowered cost of both stable and radioactive isotopes has made possible study...

The total body water and the water turnover in pregnancy studied with deuterium oxide as isotopic tracer.

Total body water estimations in healthy men and women using bioimpedance spectroscopy: a deuterium oxide comparison

BACKGROUND Total body water (TBW) estimations have been used to estimate body composition, particularly fat-free mass, to aid in nutritional interventions, and to monitor hydration status. In the past, bioimpedance spectroscopy (BIS) devices have been used to estimate TBW. Previous investigations have examined the validity of the XiTRON 4000B (XiTRON Technologies) BIS device for estimating TBW....

Studies of Body Water and Water Turnover Determined with Deuterium Oxide Added to Food.

In 5 dogs which ingested 25 or 50 ml. of D20 with one daily meal, maximal plasma concentrations of tracer were reached in 12-24 hr. The disappearance rate during 14 days was exponential, confirming studies of others in humans. Water turnover, calculated from values obtained for body water and the disappearance rates, agreed well with total water intake, which included water taken as such and th...